Why don't people respect the science?

Many schizophenia people have high Dopamin functions, by reducing the function the people will feel better and w
ill eventally get recovery.
There is way to reduce this function. People should eat low energy foods etc.
As a natural process, when people get aging
Their Dopamin function will decease.
Some of the people will get recover from the illness.They don't need the medication after they get 60 years old.
At least, there is an American Doctor provide us a reference.
It would benifit many people
Answer:
Schizophrenia is far more complicated than you seem to think. It does involve disregulation of the dopamine system, but it's not that there's simply too much dopamine and reducing it will restore normal function.

Antipsychotics are dopamine antagonists, which means that they block dopamine function, but they're far from a perfect cure. While they reduce the positive symptoms of schizophrenia (hallucinations, etc.), they tend to exacerbate the negative and cognative symptoms (flat emotional affect, impaired attention, poverty of speech, etc.), and can also cause deficits in motor function as a side effect even at the lowest dose that can effectively control the positive symptoms. There's some evidence that the negative symptoms may actually result from too little dopamine in certain pathways at the same time that there is too much in others. Also, there is not an excess of dompamine in pathways involved in motor control, which is why the medications can impair motor function in a manner similar to Parkinson's disease (which in non-schizophrenic patients is treated with synthetic dopamine because it results from reduced dopamine function).

Furthermore, atypical antipsychotics have shown greater success in controlling the negative and cognative symptoms of schizophrenia, and tend to produce fewer motor side effects. These compounds are serotonin antagonists as well as dopamine antagonists, and there's some evidence that disregulation of the serotonin system may also contribute to the pathology of schizophrenia. So it's not even as simple as just fixing whatever is wrong with the dopamine system - there are other systems involved as well.

It's true that some people do "out grow" schizophrenia late in life. However, symptoms typically appear when the patient is in his/her 20, so there's a pretty long time before they're in the 60+ range, and waiting isn't quite going to do it. Also, many patients do not experience reduced symptoms in old age, and some may even get worse, if they even live long enough to find out.

Finally, a low calorie diet does not regulate dopamine production, nor does it reduce the symptoms of schizophrenia. Many people with schizophrenia end up homeless, and are often undernourished, but do not experience any reduction in symptoms as a result. Actually, if anything, the stress of that situation tends to make the symptoms worse. There are currently no dietary modifications that have been shown to be effective at controlling the symptoms of schizophrenia even in combination with medication, let alone as an alternative to medication.

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I love science. Don't know why it's not respected.

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Although the chemical changes that lead to schizophrenia do indeed include (but are not limited to) excess dopamine, the disease ALSO results in permanent, STRUCTURAL changes in the brain (i.e., enlarged ventricles). Regulation of dopamine is part of the answer, to be sure. However, it is far from curative. Aging itself will not cure schizophrenia nor will it restore brain tissue. In addition, TOO LITTLE dopamine will result in parkinsonian symptoms. Although treatable, schizophrenia is a chronic psychiatric illness which is not (yet) curable.

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Schizophrenia is a very complex disorder and there is currently no chance of nailing down a cause or a solution in the near future. Dopamine antagonists (antipsychotics) seem to help, but also cause problems. Think about this: a major side-effect of these drugs are Parkinsons-like symptoms. Parkinson's disease is treated in part with L-dopa. Dopamine has a number of functions in the body and brain, such as the initiation of movement, mental planning, motivation, etc. and these take place in different pathways leading to different areas of the brain. Schizophrenia is not simply caused by "too much dopamine" and will not be resolved by depleting a person of dopamine. One reason antipsychotics are still controversial is that while they make a person more compliant and seem to help with the "positive" symptoms (delusions), that person may be simply suffering in a more compliant manner, making them easier to handle. Some of the more "negative" symptoms such as lethargy and disorganization might involve too little dopamine and/or norepinephrine in specific areas. The notion that the best route to recovery for schizophrenia is to simply adjust one's diet is a little insulting to the people living with it. I'm not sure what the purpose of your question is. Age is the cure for all suffering eventually, since it leads to death.

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People do not need the medication at all they need support and friendships. They need to have real needs met, they need good diets. That is what they really need and safety and housing and to at least be able to feel that they have some freedom and respect in our society that is what they really need.

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